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Novel marker in predicting nodal metastasis in oral squamous cell carcinoma.

Tumor Infiltrating Lymphocytes(TILs) as an independent determinant of lymph node metastasis in oral squamous cell carcinoma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/08/055965
Enrollment
110
Registered
2023-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C01- Malignant neoplasm of base of tongue Health Condition 2: C060- Malignant neoplasm of cheek mucosa Health Condition 3: C049- Malignant neoplasm of floor of mouth, unspecified Health Condition 4: C039- Malignant neoplasm of gum, unspecified Health Condition 5: C009- Malignant neoplasm of lip, unspecified Health Condition 6: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth Health Condition 7: C058- Malignant neoplasm of overlappingsites o

Interventions

Sponsors

Kasturba Medical College and Hospital, Manipal.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: T1 to T4 primary oral squamous cell cancer treated with wide excision of the tumor and simultaneous bilateral or unilateral neck dissection, depending on the tumor location and the status of the neck.Both male and female population.All age groups are included.

Exclusion criteria

Exclusion criteria: Non squamous cell carcinoma.Patients who had been previously treated with radiotherapy or chemotherapy.(neo adjuvant chemotherapy/radiotherapy)and recurrent cases of oral squamous cell carcinoma are excluded from my study.

Design outcomes

Primary

MeasureTime frame
Correlation between TILs & lymph node metastasisTimepoint: Time of diagnosis & post surgical histopathological examination final report 2 months from the time of diagnosis

Secondary

MeasureTime frame
Predicting the need for prophylactic lymph node dissection in N0 disease.Timepoint: Time of diagnosis & post surgical histopathological examination final report 2 months from the time of diagnosis

Countries

India

Contacts

Public ContactDr Nawaz Usman

Kasturba Medical College and Hospital,Manipal

rajgopal.shenoy@manipal.edu9845243460

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026