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Comparative study between diltiazem local application vs lateral sphincterotomy for anal fissure

A comparative study between diltiazem 2% gel for local application and lateral sphincterotomy for chronic fissure in ano - NIL

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/08/055934
Enrollment
100
Registered
2023-08-01
Start date
Unknown
Completion date
Unknown
Last updated
2024-01-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K601- Chronic anal fissure Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: LATERAL SPHINCTEROTOMY: The main objective of surgery in anal fissure is to alter the IAS function and prevent it from going into spasm and also to improve the anal canal diameter to ai

Sponsors

Dr Zulkarnine Ahmed
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. All patients who will present in surgical outpatient department at Silchar Medical College and Hospital with complaints of pain during defecation, irritating nature of pain around perianal region with or without bleeding for a duration of more than 6weeks, diagnosed to be having chronic anal fissure based on history and clinical examinations. 2. All previously diagnosed cases of acute anal fissure who are taking stool softener and medications for more than 6weeks

Exclusion criteria

Exclusion criteria: Chronic anal fissure associated with 1. Anorectal absecss 2. Tuberculosis 3. Anal malignancies 4. Cases with anal injuries like 4th degree perineal tear during vaginal delivery 5. Hemorrhoids 6. Patients who have undergone previous perianal surgeries

Design outcomes

Primary

MeasureTime frame
Pain relief. Relaxation of the internal sphincter. Healing of the fissureTimepoint: Patients will be reviewed on weekly basis for 1month.

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Debabrata Singha

Silchar Medical College and Hospital

debabrata.singha12@gmail.com9435072017

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026