Health Condition 1: I00-I99- Diseases of the circulatory system
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
Paveena P Kolchar
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing cardiac surgery under general anaesthesia requiring postoperative mechanical ventilation. b. Patients aged between 18-65 years. c. Patients with ASA physical status 1/2/3
Exclusion criteria
Exclusion criteria: a. Scheduled for emergency surgery b. Allergy to ascorbic acid, systemic opioids c. History of Gout d. High oxalate urine e. Uric acid kidney stone f. Glucose-6-Phosphate dehydrogenase deficiency g. Sickle cell anemia h. Thalassemia i. Pre-operative chest radiograph showing active lung disease j. Substance use disorder k. Coagulopathy l. Chronic opioid use m. Analgesic use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Incidence of post operative pulmonary complications 2.Duration of post operative ventilation 3.Duration of effective post-operative analgesiaTimepoint: 1. 0th hour, 24 hour, 48 hour, 72 hour 2. NRS- 0th min, 30 min, 2nd hour, 4th hour ,6th hour,12th hour and 24th hour | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of effective post-operative analgesiaTimepoint: Numerical Rating Score for pain is assesed at the time of shifting to PACU, 30mins, 2nd hour, 4th hour, 6th hour ,12th hour ,24th hour | — |
Countries
India
Contacts
Public ContactManjunath R Kamath
K S Hegde Medical Academy
Outcome results
None listed