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To compare effects of mango consumption in T2DM and non-diabetic subjects.

A randomized controlled study to compare effects of mango ingestion on glycemia (as per glycemic response, continuous glucose monitoring and fructosamine), insulin resistance and body composition in patients with type 2 diabetes mellitus (T2DM) and non-diabetic subjects. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055862
Enrollment
130
Registered
2023-07-31
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases

Interventions

Intervention1: Mango: 250g of mango pulp and 200ml of toned milk for 2 months in breakfast. Control Intervention1: Bread: 3 sliced of white bread and 200ml of toned milk for 2 months in breakfast.

Sponsors

Indian Council of Medical Research (ICMR)
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: For patients with diabetes: a) Stable glycemic control on metformin or sulfonyleurea for past 3 months b) without any major complication c) HbAIc less than 8%

Exclusion criteria

Exclusion criteria: For both groups a) Acute infections and advanced end-organ damage b) History of hepatitis or pancreatitis, abnormal liver and renal functions c) Recent ( d) Any known allergy to mangoes and bread e) Subjects with hypothyroidism f) On any drug causing weight gain or weight loss

Design outcomes

Primary

MeasureTime frame
1. Exploratory Acute Phase: To investigate glycemic response of mango intake by evaluating glycemic response & oral glucose tolerance testing. 2. Exploratory Sub-acute Phase: To evaluate blood glucose levels by continuous glucose monitoring system. 3. Confirmatory Chronic Phase: To determine intermediate term effect of mango ingestion on glycemia (blood glucose, fructosamine), insulin resistance (HOMA-IR, adiponectin levels) & body composition (anthropometry & TANITA scan).Timepoint: 18 months—

Secondary

MeasureTime frame
To determine intermediate term effect of mango ingestion on glycemia (blood glucose, fructosamine), insulin resistance (HOMA-IR, adiponectin levels) & body composition (anthropometry & TANITA).Timepoint: 18 months—

Countries

India

Contacts

Public ContactDr Anoop Misra

Fortis CDOC Hospital

anoopmisra@gmail.com9811153997

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026