Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sevoflurane: Sevoflurane 1-5 MAC using entropy value between 40-60 during the entire surgery
Control Intervention1: Injection Propofol: IV Infusion of Propofol 3-10mg/hour using entropy
Sponsors
Department of Anaesthesiology SMS Hospital
Eligibility
Inclusion criteria
Inclusion criteria: NYHA class II & III Ejection fraction more than 40 percent No history of nervous system disease Informed written consent
Exclusion criteria
Exclusion criteria: Hypertensive Disease Coronary Artery Disease Infective endocarditis Diabetes COPD Haematogenic and Immune Systemic Disease Perioperative Steroid Therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean Trop I Mean CP MB levels Mean IL6 Mean IL10 levelsTimepoint: Before induction 3hours after aortic unclamping 24hours & 48 hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Complications if any Timepoint: From surgery till discharge;Incidence of Intraoperative Awareness Timepoint: After extubation;Mean dose of vasoactive agents used Timepoint: Total duration of surgery;Mean duration of Mechanical ventilation Timepoint: From Induction till extubation;Mean Length of ICU / hospital stayTimepoint: From surgery to discharge;Proportion of patients with automatic heartbeat recovery Timepoint: After Cardiopulmonary Bypass | — |
Countries
India
Contacts
Public ContactSachin
SMS Medical College,Jaipur
Outcome results
None listed