Health Condition 1: P228- Other respiratory distress of newborn Health Condition 2: P220- Respiratory distress syndrome of newborn Health Condition 3: P221- Transient tachypnea of newborn
Conditions
Interventions
Intervention1: Nasopharyngeal prongs: Neonates will receive NIPPV via Nasopharyngeal prongs as an interface and will be looked for the need of intubation within 72 hours of initiation of NIPPV.
Contro
Sponsors
Dr Deepak Chawla
Eligibility
Inclusion criteria
Inclusion criteria: All inborn neonates admitted in NICU who fulfill the following criteria will be enrolled: 1. Gestation age at birth – 280/7 to 366/7 weeks 2. Receiving non-invasive positive pressure ventilation (NIPPV) for 1. A primary mode of respiratory support 2. Post- extubation respiratory support 3. Within 6 hours of initiation of NIPPV 4. Postnatal age = 28 days The neonate once randomized to the study group will remain allocated to that group for the first instance of respiratory support – for both the primary mode of respiratory support and for post-extubation support.
Exclusion criteria
Exclusion criteria: 1. Major congenital malformations 2. Pulmonary air leaks at the time of enrolment 3. Refractory shock at the time of enrolment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Need for intubation within 72 hours after initiation of NIPPVTimepoint: Need for intubation within 72 hours after initiation of NIPPV | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of invasive ventilation, NIPPV, & NCPAP (hours)Timepoint: till Hospital stay;Incidence & grade of nasal traumaTimepoint: till the use of interface for NIPPV;Need for intubationTimepoint: 72 hours to 7 days of initiation of NIPPV;Need for surfactant administrationTimepoint: till hospital stay | — |
Countries
India
Contacts
Public ContactDr Deepak Chawla
Government Medical College, Chandigarh
Outcome results
None listed