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Study of nebulised Dexmedetomidine Spinal Anaesthesia- a one year hospital based clinical trial

Study of effect of nebulised Dexmedetomidine on onset and duration of Spinal Anaesthesia- a one year hospital based randomised clinical trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055823
Enrollment
80
Registered
2023-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2024-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: Nebulized Dexmedetomidine at the dose of 1mcg/kg Body Weight is taken and diluted up to 5 ml with Normal Saline. Nebulisation is continued until the nebuliser chamber i

Sponsors

Other
Lead Sponsor
Dr Vandana Gogate
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I to II Patients undergoing elective infra-umbilical surgery under Spinal Anaesthesia

Exclusion criteria

Exclusion criteria: Patients with ASA Grade III and above Patients contraindication to Spinal Anaesthesia Patients with known allergy to Dexmedetomidine Patients on pre-operative drugs that could be potential confounders such as Clonidine, Gabapentin, Pregabalin, Steroids etc.

Design outcomes

Primary

MeasureTime frame
To study the effect of nebulised Dexmedetomidine on onset and duration of sensor and motor block in Spinal AnaesthesiaTimepoint: Monitored every 5 min upto 30 minutes then every 10 minutes upto the end of surgery

Secondary

MeasureTime frame
Time for first rescue analgesia Total analgesic requirement in the first 24 hours post-operatively To study the side effects of the drug, if anyTimepoint: Monitored every 5 min upto 30 minutes then every 10 minutes upto the end of surgery

Countries

India

Contacts

Public ContactRishabh G Mankale

Jawaharlal Nehru Medical College, Belagavi

vandanagogate@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026