6% hydroxyethyl starch for reduction of pain of propofol injection.

Comparison of the efficacy of 6% Hydroxyethyl starch and 2% Lidocaine in reducing the pain of propofol injection.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055821

Enrollment

339

Registered

2023-07-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: pre-administration of 6% HES and 2% lignocaine before propofol administration.: the pain of propofol administration was compared when propofol was pre-administered with 6% HES and 2% l

Eligibility

Inclusion criteria

Inclusion criteria: All adult ASA-PS I, II patients undergoing elective surgeries under general anesthesia at Chirayu Medical College & Hospital, Bhopal.

Exclusion criteria

Exclusion criteria: 1. Emergency surgeries 2. Patients with pre-existing chronic renal failure (GFR 3. Patients with pre-existing liver diseases 4. Patients with pre-existing severe cardiac diseases (EF 5. Patients in whom hand or forearm veins are not-accessible 6. Patients’ refusal to participate in study.

Design outcomes

Primary

Measure	Time frame
To compare the incidence and severity of Pain Of Propofol Injection in patients pre-administered with either HES or 2% Lidocaine during induction of anesthesia with propofol.Timepoint: 10 seconds after propofol administration	—

Secondary

Measure	Time frame
3. To compare the hemodynamic profile of patients after induction in the study groups.Timepoint: Baseline, post-induction	—

Countries

India

Contacts

Public ContactSAURABH TRIVEDI

CMCH Bhopal

drst23@gmail.com7042461338

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026