To compare the effectiveness of needling with 5-fluorouracil 5% cream versus topical 88% phenol application in the treatment of vitiligo

Prospective randomized comparative study of therapeutic efficacy of microneedling with 5-fluorouracil 5% cream versus topical 88% phenol application in the treatment of vitiligo - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055803

Enrollment

Registered

2023-07-28

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80- Vitiligo

Interventions

Intervention1: Microneedling with 5-fluorouracil 5 % cream in the treatment of vitiligo: For patients with vitiligo 5-fluorouracil 5% cream with microneedling given at baseline then every 2 weeks for

Eligibility

Inclusion criteria

Inclusion criteria: Patients with clinical diagnosis of stable vitiligo Patients who are willing to participate in the study

Exclusion criteria

Exclusion criteria: Patients with unstable vitiligo Patients allergic to 5-fluorouracil 5% cream and 88% phenol Patients with predisposition to keloids Patients and lactating mothers Patients not willing for procedures

Design outcomes

Primary

Measure	Time frame
Compare the clinical response by repigmentation to microneedling with 5-fluorouracil 5% cream and topical 88% phenol application in the treatment of vitiligoTimepoint: At the end of 3 months, and 6 months	—

Secondary

Measure	Time frame
Treatment side effectsTimepoint: Every 4 weeks for 3 months	—

Countries

India

Contacts

Public ContactDr. VISMITHA S E

VINAYAKA MISSIONS MEDICAL COLLEGE, KARAIKAL

hoddvdvmmckkl@gmail.com9884835199

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026