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To compare the effect of scalp nerve block and local anaesthetic infiltration together and with local anaesthetic infiltration alone on inflammatory response in patients undergoing elective neurosurgery.

Comparison of scalp nerve block and local anaesthetic infiltration with local anaesthetic infiltration alone on inflammatory response in patients undergoing elective neurosurgery.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055799
Enrollment
90
Registered
2023-07-28
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G939- Disorder of brain, unspecified Health Condition 2: G94- Other disorders of brain in diseases classified elsewhere Health Condition 3: G94- Other disorders of brain in diseases classified elsewhere

Interventions

Intervention1: Effect of Scalp nerve block and Local anaesthetic infiltration on inflammatory response: Application of scalp nerve block and local anaesthetic infiltration in patients undergoing elect

Sponsors

Vardhman Mahavir medical college and Safdarjung hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists physical status I-II Scheduled for elective neurosurgery.

Exclusion criteria

Exclusion criteria: 1. Distorted surgical anatomy of Scalp. 2. Previous craniotomy incision. 3. History of allergy to opioids or local anaesthetics. 4. Unable to understand Visual Analog Scale.

Design outcomes

Primary

MeasureTime frame
To compare scalp nerve block & local anaesthetic infiltration with local anaesthetic infiltration alone in patients undergoing elective neurosurgery by means of bio markers C-Reactive Protein, Interleukin 6 & Interleukin 10Timepoint: Baseline , Immediately postoperatively & at 24 hours of surgery—

Secondary

MeasureTime frame
To compare hemodynamic stability by means of heart rate & blood pressure ( mean arterial pressure) Timepoint: A. Before Anaesthesia induction, 5 minutes after skin incision,during dura opening ,at the end of surgery;To compare the postoperative pain by means of Visual Analog ScaleTimepoint: Immediately postoperative period & at 12 hours of surgery—

Countries

India

Contacts

Public ContactMeenakshi Kumar

Vardhman Mahavir medical college and Safdarjung hospital

drmeenakshi86@yahoo.com9899689829

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026