Comparing three methods of giving oxygen before anaesthesia using simple face mask and high flow nasal oxygen device in lying down versus head up position in patients undergoing abdominal surgeries

Efficacy of head up position versus supine position with high flow nasal oxygenation compared with conventional preoxygenation in patients undergoing exploratory laparotomy: A randomised controlled study - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055747

Enrollment

Registered

2023-07-27

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K659- Peritonitis, unspecified

Interventions

Intervention1: HFNO HU: In each patient , an arterial line will be secured after performing the modified allens test . A baseline ABG sample will be taken before the start of anaesthesia . Each patien

Eligibility

Inclusion criteria

Inclusion criteria: Patients with peritonitis undergoing Exploratory Laparotomy. Patients >=18 years of age. Patients who have given consent.

Exclusion criteria

Exclusion criteria: Pregnant women. Hemodynamically unstable patients. Patient in need of non-invasive ventilation. Unconscious patients. Patients requiring emergency intubation. Psychiatric Patients. Patient with severe cardiovascular disease.

Design outcomes

Primary

Measure	Time frame
To compare the change in PaO2 after 5 mins of preoxygenation with HFNO with 25 degrees head up position versus HFNO in supine AND conventional preoxygenation using face mask.Timepoint: To compare the change in PaO2 after 5 mins of preoxygenation with HFNO with 25 degrees head up position versus HFNO in supine AND conventional preoxygenation using face mask.	—

Secondary

Measure	Time frame
To compare between the three groups: 1.Saturation of oxygen (SpO2) after preoxygenation. 2.SpO2 after 1 minute of intubation. 3.Lowest Spo2 from the start of preoxygenation to after 1 minute of intubation. 4.Incidence of desaturation (SpO2 93%) from the end of preoxygenation to intubation. 5.PaO2 after1 min of intubation. 6.PaCO2 after 1 min of intubation. 7.Tolerance of the patient for the device. 8.Anesthesiologistâ??s satisfaction using 5point Likert scale. 9.Duration of laryngoscopy in the three groups. 10.Duration of Intubation in all the groups. 11.Hemodynamic parameters after preoxygenation. 12.Hemodynamic parameters post-intubation. Timepoint: 1.After 5 minutes of preoxygenation 2.After 1 minute of intubation 3.Start of preoxygenation to after 1 minute of intubation 4.End of 5 minutes of preoxygenation to intubation 5.Till extubation	—

Measure

Time frame

To compare between the three groups: 1.Saturation of oxygen (SpO2) after preoxygenation. 2.SpO2 after 1 minute of intubation. 3.Lowest Spo2 from the start of preoxygenation to after 1 minute of intubation. 4.Incidence of desaturation (SpO2 93%) from the end of preoxygenation to intubation. 5.PaO2 after1 min of intubation. 6.PaCO2 after 1 min of intubation. 7.Tolerance of the patient for the device. 8.Anesthesiologistâ??s satisfaction using 5point Likert scale. 9.Duration of laryngoscopy in the three groups. 10.Duration of Intubation in all the groups. 11.Hemodynamic parameters after preoxygenation. 12.Hemodynamic parameters post-intubation. Timepoint: 1.After 5 minutes of preoxygenation 2.After 1 minute of intubation 3.Start of preoxygenation to after 1 minute of intubation 4.End of 5 minutes of preoxygenation to intubation 5.Till extubation

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Countries

India

Contacts

Public ContactDr Priyatosh

UCMS and GTB Hospital

rudoc@rediffmail.com9560678023

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026