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To compare the difference in blood pressure caused by two different local anaesthetic drugs given for spinal anaesthesia in patients undergoing lower abdominal and lower limb surgeries.

COMPARISON OF HEMODYNAMIC IMPACT OF HYPERBARIC LEVOBUPIVACAINE+BUPRENORPHINE Vs HYPERBARIC BUPIVACAINE+BUPRENORPHINE FOR SPINAL ANAESTHESIA IN PATIENTS UNDERGOING INFRAUMBILICAL SURGERIES : A DOUBLE BLIND RANDOMIZED CLINICAL STUDY.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055729
Enrollment
54
Registered
2023-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N819- Female genital prolapse, unspecified Health Condition 2: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Inj Hyperbaric Levobupivacaine: 15 mg of 0.5% inj hyperbaric levobupivacaine+ inj buprenorphine (2mcg/kg) for spinal anaesthesia Control Intervention1: Inj Hyperbaric bupivacaine: 15mg

Sponsors

Dr Kalaivani S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)American society of Anaesthesiologists(ASA) physical status classification 1 and 2. 2) scheduled for elective infraumbilical surgeries under regional anaesthesia 3)patients with valid informed consent

Exclusion criteria

Exclusion criteria: 1)Patient refusal for regional anaesthesia 2)emergency infraumbilical surgeries 3)patients having hypersensitivity to any of the study drugs 4)patients with spinal deformities 5)preexisting neurological diseases like lower extremity neuropathy 6)intrinsic or idiopathic coagulopathy 7)skin or soft tissue infection at proposed site of needle insertion

Design outcomes

Primary

MeasureTime frame
To compare difference in systolic blood pressure between two study groupsTimepoint: to check for blood pressure every 5 minutes once until the end of surgery

Secondary

MeasureTime frame
Degree of motor blockade achievedTimepoint: degree of motor blockade checked every 2 minutes upto 10 minutes after spinal anaesthesia;onset of sensory blockTimepoint: sensory level checked every 2 minutes upto 10 minutes after spinal anaesthesia;total duration of analgesiaTimepoint: to check the total duration of analgesia achieved after spinal anaestheia

Countries

India

Contacts

Public ContactDr Pushpavathi S H

Karnataka institute of medical sciences

pushpadrture@rediffmail.com9448251597

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026