Health Condition 1: N189- Chronic kidney disease, unspecified
Conditions
Interventions
None listed
Sponsors
Dr Shruti Bhide
Eligibility
Inclusion criteria
Inclusion criteria: 1. Persistent proteinuria >300mg/dl 2. Male or Female >18 year of age
Exclusion criteria
Exclusion criteria: 1.Type 1 diabetes 2.Type 2 diabetes 3.Active malignancy 4.Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1a. Percentage reduction in Proteinuria at the end of 1 year in non-diabetic proteinuric kidney diseases patients after 1 year of treatment with SGLT2 inhibitors. 1b. Percentage reduction in Proteinuria at the end of 3 years in non-diabetic proteinuric kidney diseases patients after 3 years of treatment with SGLT2 inhibitors.Timepoint: 1 year & 3 year | — |
Secondary
| Measure | Time frame |
|---|---|
| 2a. Percentage of patients with =25% & =50% decrease of eGFR from the baseline at the end of 1 year in non-diabetic proteinuric kidney diseases patients after 1 year of treatment with SGLT2 inhibitors. 2b. Percentage of patients =25% and =50% decrease of eGFR from the baseline at the end of 3 years in non-diabetic proteinuric kidney diseases patients after 3 years of treatment with SGLT2 inhibitors. 3. Time to doubling of serum creatinine 4. Percentage of patients developing ESRD 5. Percentage of patients developing adverse drug reactions leading to discontinuation of SGLT2 inhibitors.Timepoint: 1 year & 3 year | — |
Countries
India
Contacts
Public ContactShruti Bhide
Seth GS Medical College and KEM hospital, Mumabai
Outcome results
None listed