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TO MEASURE THE EFFECT OF REDUCTION IN PAIN ON PROPOFOL INJECTION AFTER ADMINISTRATION OF 6% HYDROXYETHYL STARCH VS 2% LIDOCAINE.

TO COMPARE THE EFFECT OF REDUCTION IN PAIN ON PROPOFOL INJECTION AFTER ADMINISTRATION OF 6% HYDROXYETHYL STARCH VS 2% LIDOCAINE.

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055719
Enrollment
70
Registered
2023-07-26
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Control Intervention1: 2% Lignocaine: To compare the decrease in pain on Propofol injection with pre administration of starch vs lignocaine Control Intervention2: 6%hydroxy ethyl starch: To compare th

Sponsors

Dr Merlyn Varghese
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.adult patient with ASA 1 and 2 class 2.patients between the age group 18-55 years old, of either gender 3.patients undergoing elective surgery under general anaesthesia

Exclusion criteria

Exclusion criteria: 1.All emergency surgeries 2.ASA class 3 and 4 3.Paediatric population 4.pregnant individuals 5.known history of allergy to propofol or HES 6.presence of severe left ventricular dysfucntion 7.hand or forearm veins not accessible

Design outcomes

Primary

MeasureTime frame
1.haemodynamic variables: heart rate,Systolic blood pressure,Diastolic blood pressure and mean arterial pressure 2.severity of pain 3.incidence of pain 4.Pain scoreTimepoint: 10 seconds 20 seconds 30 seconds 40 seconds till loss of verbal contact

Secondary

MeasureTime frame
incidence of side effects/adverse effects like 1)pruritus 2)chills 3)anaphylactoid reaction 4)hypersensitivity reactionsTimepoint: if occurence of any such event it will be noted

Countries

India

Contacts

Public ContactDr Suresh Y V

Kasturba Medical College

sureshyv63@gmail.com9845085108

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026