A clinical trial to study the effects of the combination of modified Buerger-Allen exercise with Epsom-salt foot bath for the management of Chemotherapy-Induced peripheral neuropathy among breast cancer patients

Evaluation of comparative efficacy of the combination of modified Buerger-Allen exercise and Epsom salt foot bath as against modified Buerger-Allen exercise and Epsom-salt foot bath alone, for the management of chemotherapy induced peripheral neuropathy in breast cancer patients - Nil

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055716

Enrollment

180

Registered

2023-07-26

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: C50- Malignant neoplasm of breast

Interventions

Intervention1: Burger-Allen exercise: The BAE includes three steps: (1) lie down on the bed, raise the legs between 45 and 60 degrees for one minute supported by a pillow, and maintain that position f

(2) sit up at the bedside, move the foot from extension to flexion, and then change position from the posterior varus to valgus for 3 min

and (3) lie down and warm the legs using a blanket for 3 min. Participants had to repeat the above three steps for three cycles twice a day immediately after waking up and before retiring. Interventio

and (3) lie down and warm the legs using a blanket for 3 min. Participants had to repeat the above three steps for three cycles twice a day immediately after waking up and before retir

Eligibility

Inclusion criteria

Inclusion criteria: Symptomatic CIPN Breast cancer patients and asymptomatic CIPN breast cancer patients.

Exclusion criteria

Exclusion criteria: 1. Patients who are terminally ill and having psychiatric conditions. 2. Patients who are suffering from diabetes, Diabetic neuropathy and other neurological symptoms. 3. Patients suffering from any other musculoskeletal disorders.

Design outcomes

Primary

Measure	Time frame
Buergers Allen exercise with Epsom salt foot bath may be used as an effective non pharmacological measures to treat chemotherapy induced peripheral neuropathy for breast cancer patients compared to BAE & Epsom salt foot bath alone Timepoint: 2nd / 3rd cycle chemotherapy for the baseline assessment and following assessment on 4th, 5th, and 6th cycle for symptomatic cases and 1st cycle chemotherapy for the baseline assessment and following assessment on 2nd, 3rd, 4th, 5th, and 6th assessment for asymptomatic cases	—

Measure

Time frame

Buergers Allen exercise with Epsom salt foot bath may be used as an effective non pharmacological measures to treat chemotherapy induced peripheral neuropathy for breast cancer patients compared to BAE & Epsom salt foot bath alone Timepoint: 2nd / 3rd cycle chemotherapy for the baseline assessment and following assessment on 4th, 5th, and 6th cycle for symptomatic cases and 1st cycle chemotherapy for the baseline assessment and following assessment on 2nd, 3rd, 4th, 5th, and 6th assessment for asymptomatic cases

—

Secondary

Measure	Time frame
The combination of modified Buerger-Allen exercise & Epsom-salt foot bath may also improve the overall quality of life of breast cancer patients during chemotherapyTimepoint: The quality of life will be checked in both symptomatic & asymptomatic breast cancer patients after each cycle of chemotherapy. 2nd / 3rd cycle chemotherapy for the baseline assessment & following assessment on 4th, 5th, & 6th cycle for symptomatic cases & 1st cycle chemotherapy for the baseline assessment & following assessment on 2nd, 3rd, 4th, 5th, & 6th assessment for asymptomatic cases.	—

Measure

Time frame

The combination of modified Buerger-Allen exercise & Epsom-salt foot bath may also improve the overall quality of life of breast cancer patients during chemotherapyTimepoint: The quality of life will be checked in both symptomatic & asymptomatic breast cancer patients after each cycle of chemotherapy. 2nd / 3rd cycle chemotherapy for the baseline assessment & following assessment on 4th, 5th, & 6th cycle for symptomatic cases & 1st cycle chemotherapy for the baseline assessment & following assessment on 2nd, 3rd, 4th, 5th, & 6th assessment for asymptomatic cases.

—

Countries

India

Contacts

Public ContactRahul shil

ruchira.shende@rediffmail.com7620978673

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026