Repetitive Transcranial Magnetic Stimulation with Virtual Reality Training to improve sensory-motor and cognitive deficits among stroke patients

Efficacy of simultaneous application of Repetitive Transcranial Magnetic Stimulation and Virtual Reality Training on sensory-motor and cognitive deficits among stroke patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055713

Enrollment

Registered

2023-07-26

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I693- Sequelae of cerebral infarction Health Condition 2: I698- Sequelae of other cerebrovasculardiseases

Interventions

Intervention1: Simultaneous application of Repetitive Transcranial Magnetic Stimulation along with virtual reality training.: In this double-blind protocol, participants are assigned to either receive

Eligibility

Inclusion criteria

Inclusion criteria: The first-ever unilateral stroke diagnosed by imaging The course of the disease ranged from 2 weeks to 6 months. UL dysfunction as indicated by the Fugl-Meyer motor function score Aged 40â??70 years, regardless of sex. No severe cognitive or communication impairment as indicated by the Mini-mental state examination (MMSE) >= 24 points.

Exclusion criteria

Exclusion criteria: Severe aphasia (score of 2 points in the national institute of health stroke score (NIHSS) language item assessment), Moderate to severe cognitive impairment (score of 15 points in a mini-mental state examination assessment), Shoulder subluxation or shoulder pain >4 points in the numerical visual scale of pain, Uncontrolled epilepsy or epilepsy episodes in the last 3 months, having any other underlying neurological disease, severe aphasia Â or cognitive impairment; Having any contraindications to TMS and/or MRI, such as having cardiac pacemaker, metal foreign bodies , any cranial metallic implants, a history of neurosurgery, other electronic devices implanted in the body, as according to the safety guidelines, they are contraindications for TMS, such as or other electronic devices implanted in the body, etc. Application of drugs that change the excitability of the cerebral cortex.

Design outcomes

Primary

Measure	Time frame
The Motricity Index Fugl-Meyer Assessment (FMA) scale Mini Mental State Examination (MMSE) ADDENBROOKES COGNITIVE EXAMINATION - (ACE-III) The National Institutes of Health Stroke Scale (NIHSS)Timepoint: baseline, After 4 weeks (12 sessions) 3 sessions per week (Monday, Wednesday, Friday)	—

Secondary

Measure	Time frame
Functional AssessmentTimepoint: o day 24th day	—

Countries

India

Contacts

Public ContactPRIYA CHAUHAN

AMITY UNIVERSITY

skdas@amity.edu8879485847

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026