To study the effect of Panchakarma Essential (Nirgundi-based formulation) in Knee Osteoarthritis.

A Clinical Study to Evaluate the Safety and Efficacy of Panchakarma Essential (Nirgundi-based formulation) in reducing symptoms of Knee Osteoarthritis. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055689

Enrollment

Registered

2023-07-26

Start date

Unknown

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Nirgundi oil as per Panchakarma Essential: Use of Panchakarma Essential to performing panchakarma process as per investigator discretion Control Intervention1: Standard Practice of Panc

Eligibility

Inclusion criteria

Inclusion criteria: 1. Male and female subjects 30-60 years of age (both inclusive) 2. The patient diagnosed with an OA of the knee for greater than 3 months 3. VAS (visual analog scale) score during the most painful knee movement between 40-70 mm. 4. Subjects with or without consuming analgesics and anti-inflammatory medicines. 5. Willing to refrain from taking ibuprofen, aspirin, other NSAIDs, or any other pain reliever (OTC or prescription) during the entire trial. 6. Ambulatory subject able to provide verbal and written consent and ready to comply with all study procedures.

Exclusion criteria

Exclusion criteria: 1. Female subjects, who are pregnant, breastfeeding, or planning to become pregnant. 2. Recent injury in the area affected by OA of the knee (past 4 months) 4. History of underlying inflammatory arthropathy or severe OA (VAS score greater than 70) 5. Have taken any intra-articular treatment/injections with a corticosteroid or hyaluronic acid within 6 months preceding the treatment period. 6. History of psychiatric disorder that may impair the ability of subjects to provide written informed consent 7. Participation in any osteoarthritis related trials involving investigational products within 30 days prior to the screening Visit.

Design outcomes

Primary

Measure	Time frame
1. To study the efficacy of Panchakarma Essential on Osteoarthritis. 2. To assess the reduction in knee pain & inflammation.Timepoint: 1. Seven Sessions in two weeks 2. Post treatment follow up for 2 weeks	—

Secondary

Measure	Time frame
1. To study the dependency of analgesics to manage pain in osteoarthritis. 2. To assess the improvement in the Quality of life of a patient Timepoint: 1. Seven Sessions in two weeks 2. Post treatment follow up for 2 weeks	—

Countries

India

Contacts

Public ContactDr Vaishnavi Patil

Mprex Healthcare Pvt. Ltd.

vaishnavi@mprex.in9834585994

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026