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Can we predict the need for blood transfusions and admissions to the ICU sooner with a simple quick blood investigation, sent upon arrival to the hospital, in patients who have experienced multiple physical injuries?

Initial lactate and base deficit values as predictors for blood transfusion, ICU admission and mortality within 48 hours in polytrauma cases - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055664
Enrollment
91
Registered
2023-07-25
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S00-T88- Injury, poisoning and certain other consequences of external causes

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

M S Ramaiah Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Adults, both males and females aged between 18 to 70 years of age, who have encountered polytrauma less than 12 hours prior to admission and who will have an injury severity score of >16

Exclusion criteria

Exclusion criteria: a) Poly trauma cases that have received prior treatment for more than 6 hours in a tertiary care centre and then been shifted/sent to this hospital for further management b) Patients who have already received blood transfusion c) Patients who are on anti coagulants or dual anti platelet therapy d) Patients with severe traumatic brain injury e) Jehovas witnesses f) Patients with burns, known hepatic disorders, renal failure, malignancy, shock due to spinal trauma, pre-hospital cardiac arrest, drug poisoning g) patients who refuse treatment, h) Pregnant women i) Conditions predisposing to altered lactate levels: heart failure, respiratory failure, liver disease, severe dehydration

Design outcomes

Primary

MeasureTime frame
a)Requirement for Blood transfusion- If blood has been transfused, i.At what value of haemoglobin was the blood transfused ii.Whether whole blood or only packed cells was transfused (transfusion of other blood products will not be included in the study) iii.Whether massive transfusion protocol was initiated or not Timepoint: At the end of 48 hours

Secondary

MeasureTime frame
A) Death B) ICU admission C) Whether the patient has been taken up for any emergency unplanned surgical procedure (elective procedures will not be included in the study) Within 48 hours of admission Timepoint: At the end of 48 hours

Countries

India

Contacts

Public ContactDr Thejeswini

M S Ramaiah Medical College

thejummc@gmail.com9480147918

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026