Health Condition 1: C00-D49- Neoplasms
Conditions
Interventions
Intervention1: To give intravenous iron formulation Ferric carboxymaltose for patients with HB less than 8g/dl and proven iron defeciency anemia in patients undergoing major oncological surgeries.: Co
Sponsors
Basavatarakam Indo American Cancer Hospital & Research Institute
Eligibility
Inclusion criteria
Inclusion criteria: 1. Major elective abdominal surgeries 2. ASA I-III 3. Hemoglobin concentration less than 8.5 g/dL
Exclusion criteria
Exclusion criteria: 1. Laboratory test confirmed iron deficiency: serum ferritin >30mcg/L alone or serum ferritin 30-100mcg/L with TSAT >20% 2. Other known causes of anaemia apart from iron deficiency 3. chronic renal failure on dialysis 4. Chronic liver failure 5. Presence of iron overload ; known hemochromatosis / Thalassemias 6. Known hypersensitivity towards Ferric carboxymaltose 7. Participation in another ongoing other interventional clinical trial(s) 8. Patients undergoing emergency surgeries 9. Significant Coronary artery disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of IV iron administration to improve preoperative hemoglobin concentrationTimepoint: to evaluate hemoglobin levels one day prior to surgery & on postoperative days 1 & 2. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine the effect of preoperative intravenous iron supplementation therapy on the need for perioperative blood transfusions. 2. To determine the effect of preoperative IV iron supplementation on serum phosphate levels a day prior to the surgeryTimepoint: requirement of blood transfusion in the postoperative period & to evaluate phosphate levels one day prior to surgery & on post operative day 3 | — |
Countries
India
Contacts
Public ContactDr Pratiksha
Basavatarakam IndoAmerican Cancer Hopsital and Research institute
Outcome results
None listed