Health Condition 1: C539- Malignant neoplasm of cervix uteri, unspecified
Conditions
Interventions
Intervention1: RADIOTHERAPY DELIVERY TECHNIQUE: DOSE ESCALATED INTENSITY-MODULATED RADIOTHERAPY (SIB-IMRT)
Intervention2: Dose escalated intensity-modulated radiotherapy.: Dose escalated intensity-mod
Sponsors
Dr Anjan Bera
Eligibility
Inclusion criteria
Inclusion criteria: Age- 30 to 70 years Histologically confirmed non-metastatic loco-regionally advanced carcinoma of the cervix (FIGO Stage- IIB-IVA Adequate hematological functions Adequate hepatic, renal function, and cardiac evaluation ECOG performance status 0-3 Participants can understand and sign informed Consent for the study
Exclusion criteria
Exclusion criteria: Any medical condition that precludes delivery of Radiation Therapy/ Concurrent Chemotherapy Metastatic Cervical carcinoma Patients unable to answer or unable to provide subjective information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sample size as calculated could be recruited, Better tumor response, disease free survival, better overall survival Reasonably low levels of treatment-related toxicities.Timepoint: To evaluate the tumor response at 12 weeks after completion treatment, then 4 monthly and last follow up. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the radiotherapy-related acute & late toxicities in these patients.Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactDEBASMITA CHAKRABARTI
NRS Medical College and Hospital
Outcome results
None listed