Health Condition 1: E116- Type 2 diabetes mellitus with other specified complications
Conditions
Interventions
Control Intervention1: Case Control: A total of 125 diabetic foot ulcer patients (25 in each group) and 125 diabetic patients without foot ulcer of both sex admitted to surgery wards will be screened
Sponsors
Dr Shaheen B Shaikh
Eligibility
Inclusion criteria
Inclusion criteria: A total of 125 diabetic foot ulcer patients and 125 diabetic patients without foot ulcer (free from foot wounds and acute or chronic disease), admitted to surgery wards will be enrolled in the study. All wounds will be graded when they will get admitted to the hospital according to the Wagner classification system into five grades (grade I - grade V), the number of patients in each group will be 25.Foot ulcer was defined as a full-thickness skin defect that required >=14 days for healing. Cases and controls will be matched for age (±3 years), sex and duration of Diabetes.
Exclusion criteria
Exclusion criteria: Patients with inflammatory or infectious diseases, autoimmune and rheumatic diseases, cancer, hematological diseases, malignancy, Pregnancy ,lactation ,Chronic inflammatory disorders, severe renal or liver failure, recent venous thromboembolism ,as well as those who were under treatment with immunodeficiency drugs , will be excluded from study . Foot ulcers caused by other conditions such as arterial insufficiency, venous insufficiency, or trauma will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the study may provide new insights that could lead to better diagnosis, prevention, & treatment of this condition, ultimately improving the health outcomes & well-being of affected individuals.Timepoint: At Baseline, 4 weeks and 8 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| This study can also raise the possibility that inflammatory markers might provide an adjunctive method for early detection of risk for this disease & ultimately decreases the lower limb amputation & hence decreasing the mortality & morbidity of patients with DFU.Timepoint: At Baseline, 4 weeks & 8 weeks | — |
Countries
India
Contacts
Public ContactDr Shaheen B Shaikh
Yenepoya Medical College Hospital
Outcome results
None listed