Health Condition 1: K135- Oral submucous fibrosis
Conditions
Interventions
Intervention1: Curcumin: 300mg of curcumin is given thrice daily for 3 months and the patient is followed up at 15 days regular intervals.
Control Intervention1: Lycopene: 20000mcg of lycopene is give
Sponsors
Sardar Patel Post Graduate Institute of Dental and Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1- Clinically diagnose case of OSMF 2- Patients who are willing for participation 3- Patients between the age group of 18 to 80 years of age
Exclusion criteria
Exclusion criteria: 1- Patients below 18 years of age. 2- Any development anamolies like bifid uvula, cleft palate. 3- Any syndromic cases. 4- Trismus due to other causes like abscess, space infections. 5- Restricted mouth opening due to trauma, impacted teeth, TMJ pathologies. 6- Patients who have undergone any surgical treatment like surgeries for carcinoma or any other surgery. 7- Patient with history of radiotherapy. 8- Pregnant females. 9- Patient who are not willing to participate. 10- Patient with known allergy to curcumin & lycopene
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lycopene and curcumin could be considered be a safe and effective therapeutic modality for patients with a chronic condition like OSMF. The primary outcome is to see which is more effective.Timepoint: Baseline 1 months 3 months 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| To observe any efficacy of these drugs among genders & at different age groups Timepoint: Baseline 2 weeks 4 weeks 8 weeks 6 months | — |
Countries
India
Contacts
Public ContactAnjali yadav
Sardar patel post graduate institute of dental and medical sciences
Outcome results
None listed