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Effect of different Local anesthetics in patients having high blood pressure with tooth pain.

â??COMPARATIVE EVALUATION OF EFFICACY OF 2% LIGNOCAINE AND 3% MEPIVACAINE IN ACHIEVING PULPAL ANAESTHESIA IN CONTROLLED HYPERTENSIVE PATIENTS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS ?- A RANDOMIZED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055567
Enrollment
92
Registered
2023-07-24
Start date
Unknown
Completion date
Unknown
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension Health Condition 2: I10- Essential (primary) hypertension Health Condition 3: O- Medical and Surgical

Interventions

Intervention1: 3% mepivacaine plain: 3%mepivacaine plain will be administered in controlled hypertensive and normal patients by inferior alveolar nerve block technique for 1 min. Control Intervention1

Sponsors

Shanmugapriya K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Able to provide informed consent. 2. Carious mandibular molars with diagnosis of symptomatic irreversible Pulpitis. 3. Patients who will be currently experiencing active pain in mandibular molars. 4. Participants should not be under any medications that would alter pain perception. 5. The patients should be clinically diagnosed with irreversible pulpitis, determined by spontaneous pain and prolonged response to cold testing with Endofrost (Coltene- Roeko) and a positive response to electric pulp testing, with absence of any periapical radiolucency on radiographs except for a mild widening of periodontal ligament space and a vital coronal pulp on access opening. 6. Every patient should have at least one opposing or contralateral molar without any deep coronal restoration, extensive caries, periodontal disease, which will be used as a control while pulp testing. 7. Blood pressure should be in the range of 120/80mm Hg to 160/100mm Hg.

Exclusion criteria

Exclusion criteria: 1. Allergies to local anaesthetics or sulphites. 2. Below the age of 18 years. 3. History of significant medical conditions. 4. Taking any medication, which may affect the pain assessment. 5. Active periapical pathosis. 6. Pregnant and Lactating women. 7. Mandibular molars without vital pulp tissue will be later excluded during endodontic procedures.

Design outcomes

Primary

MeasureTime frame
efficacy of pulpal anesthesia with 3% mepivacaine and 2%lignocaineTimepoint: 3to 8mins after administration of the local anaesthesia and after each procedure the efficacy of the drug will be checked until the end of the procedure

Secondary

MeasureTime frame
onset of pulpal anesthesiaTimepoint: 2 mins after the administration of the local anesthesia, with electric pulp tester , onset will be determined .

Countries

India

Contacts

Public ContactShanmugapriya K

RVS dental college and hospital

gvink74@gmail.com9176936752

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026