A comparison of the change in stretchability of lung and post-operative collapse of lung detected by lung USG among adults after cardiac surgery undergoing alveolar recruitment maneuvers in ICU with existing standard of care - a randomized controlled trial

A comparison of change in compliance and incidence of postoperative atelectasis detected by Lung USG among adults after cardiac surgery undergoing alveolar recruitment manoeuvres after ICU admission with that of existing standard of care: A randomised controlled trial - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055560

Enrollment

Registered

2023-07-24

Start date

Unknown

Completion date

Unknown

Last updated

2024-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I20-I25- Ischemic heart diseases Health Condition 2: I20-I25- Ischemic heart diseases

Interventions

Intervention1: alveolar recruitment manoveure: PEEP with best compliance will be determined after alveolar recruitment maneuvre and applied for 2 hours. Control Intervention1: Standard institutional p

Eligibility

Inclusion criteria

Inclusion criteria: 1. patients consenting/willing to participate in the study 2. ASA I, II ,III 3. Elective cardiac surgery using cardiopulmonary bypass

Exclusion criteria

Exclusion criteria: 1. Not consenting to participate in the study 2. pregnancy 3. on hormonal therapy 4. previous procedures like heart transplant, Pulmonary thrombectomy, aortic arch and other deep dynamic hypoyhermic circulatory arrest surgeriesand concomittent other non cardiac interventions 5. severe pulmonary diseases requiring preoperative inhaled and oral therapies ( interstitial lung disease, chronic bronchitis, airway obstruction, tumor, inflammatory disorders and other lung pathologies 6. patients undergoing deep hypothermic circulatory arrest during surgery 7. emergency surgery 8. EURO score II > 80 % 9. BMI >34.9 Kg/m2 10. diaphragmatic and respiratory muscle dysfunction(amyotrophy,neurological or neuro muscular) 11.chest wall deformity 12.cardiac arrythmias 13.cardiac surgery combined with pulmonary resection

Design outcomes

Primary

Measure	Time frame
1. change in lung compliance (dynamic & static) 2. change in atelectasis lung ultrasound scoreTimepoint: - Both parameters at Baseline - lung compliance (dynamic & static) every 15 min for two hours after alveolar recruitment maneuver - Lung ultrasound score at end of 2 hours after alveolar recruitment maneuver	—

Secondary

Measure	Time frame
tidal volume ETCO2 PEEP SPO2 VIS P/F Ratio Aa DO2 SaO2 PaCO2 PaO2Timepoint: Every 15 min for first 2hours after alveolar recruitment maneuver	—

Countries

India

Contacts

Public ContactDr Rahul Yadav

Armed Forces Medical College

bhargavadv@gmail.com8135855155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026