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Comparative Clinical Efficacy Of Different desensitizing Agents At Relieving Dentin Hypersensitivity : A Patient Reported Outcome Based Randomized Clinical Study.

"Comparison of Clinical Efficacy after Single Topical Application of 38 % Silver Diamine Fluoride (SDF), Advantage arrest, Nanoseal and Gluma at Relieving Dentin Hypersensitivity: A Patient-Reported Outcome Based Randomized Clinical Study" - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055540
Enrollment
80
Registered
2023-07-24
Start date
Unknown
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K031- Abrasion of teeth

Interventions

Intervention1: 38% silver diamine fluoride (e-SDF): Total duration : 1 minute The selected hypersensitive tooth will be dried and using a micro-brush a drop of 38% SDF will be applied on the exposed c

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Male and female patients who agreed to participate and provide written consent for the study Age group - 20-50 years Participant who have at least one non-carious cervical lesion (NCCL’s) i.e. incisor, cuspid or premolar with a buccal cervical defect and clinical hypersensitivity in response of minimum 2 on a visual analogue scale (VAS). Shallow NCCL’s- lesions that had a shallow depth (less than or equal to 0.5 mm) but their breadth and height dimensions were greater than 1.0 mm.These lesions exhibited minimal dentine exposure. Concave NCCL’s- lesions that had a greater depth than 0.5mm. Concave NCCLs did not demonstrate well-defined internal line angle. Instead, the floor of these lesions was continously curved. Generally healthy gum tissue surrounding the tooth (no ulceration or leukoplakia)

Exclusion criteria

Exclusion criteria: Any subject that does not fall under the inclusion criteria were excluded Using any desensitizing agent within one month Pharmacotherapeutic histories that may compromise the protocol - including the chronic use of anti-inflammatory, analgesic and mind-altering drugs Pregnant or lactating Periodontal surgery in the preceding 3 months

Design outcomes

Primary

MeasureTime frame
the primary outcome is the success of the treatment. Success will be measured as reduction in the dentinal hypersensitivity using Visual Analogue scale (VAS) after 1,4 & 8 weeks intervalTimepoint: 2 months

Secondary

MeasureTime frame
The secondary outcome will be patient satisfaction. Patients will complete pain assessment (labelled magnitude scale) treatment questionnaire at baseline & follow-up visits. Four factors will be considered : duration,intensity, tolerability & description)Timepoint: 2 months

Countries

India

Contacts

Public ContactDr Madhuri Patil

M A Rangoonwala college of dental sciences and research centre.

madhuribpatil89@gmail.com7507444736

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026