Assessing the impact of sweeteners on gut microbiota & telomere length in Diabetic adults

To determine the effects of Artificial sweeteners & Nutritive sweetener on the gut microbiota and its influence on the length of telomere in the adult diabetic population: Open-Labelled Prospective Randomized Controlled Trial

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055506

Enrollment

232

Registered

2023-07-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases

Interventions

Intervention1: Adult Type 2 Diabetic Population: Artificial sweeteners and a Nutritive sweetener Intervention2: Artificial Sweetener (Diabetic population): Stevia Intervention3: Artificial Sweetener

Eligibility

Inclusion criteria

Inclusion criteria: Eligible participants (age >18 years) with type 2 diabetes The participants who accept to adhere to the dietary plan and avoid consuming other sources of artificial sweeteners will be considered

Exclusion criteria

Exclusion criteria: Patients with Type 1 Diabetes Patients with Gestational Diabetes Mellitus Patients with an History of non-tolerance to artificial sweeteners Patients who consumed any artificial sweeteners prior to the study in the last 1 month Patients with malignancy, or had undergone chemo radio therapy

Design outcomes

Primary

Measure	Time frame
Artificial sweeteners, may alter the Gut Microbiota.Timepoint: 0 to 8 months	—

Secondary

Measure	Time frame
Artificial sweeteners may modulate the length of telomereTimepoint: 0 to 8 months	—

Countries

India

Contacts

Public ContactDr J S Kumar

SRM Medical College Hospital and Research Centre, SRM IST

kumarj1@srmist.edu.in9840047678

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026