Health Condition 1: S525- Fracture of lower end of radius
Conditions
Interventions
Intervention1: teriparatide hormone injection, platelet rich plasma: A subcutaneous PTH injection of 20 µg would be given to group one patients within 3 days of injury.
2ml platelet rich plasma will
Sponsors
Datta Meghe Institute of Higher Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: Closed/simple fractures of distal radius
Exclusion criteria
Exclusion criteria: 1. Polytrauma/ Ipsilateral other fractures 2. Joint diseases of ipsilateral wrist, forearm and elbow. 3. Secondary osteoporosis due to any reason. 4. Elevated serum calcium 5. Known allergy to any form of PTH hormone or analogue 6. History of a Malignant neoplasm in the 5 years prior to the study 7. Hb% less than 10gm% 8. Low platelet count 9. Any conditions evidenced to delay normal healing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Once the protocol has been applied, the groups will be followed up & outcomes will be assessed by the following methods: 1) Laboratory investigations for serum alkaline phosphatase, serially performed on day 0 within 7 days of admission & 21 days after intervention. 2) Serial radiological examination of wrist, anteroposterior and lateral views on day 0, 10, 18, 4 weeks & 6 weeks. Timepoint: On day 0 within 7 days of admission & 21 days after intervention, and on day 0, 10, 18, 4 weeks & 6 weeks. | — |
Secondary
| Measure | Time frame |
|---|---|
| fracture healing rateTimepoint: at the end of 6 weeks | — |
Countries
India
Contacts
Public ContactShraddha Sawhney
Datta Meghe Institute of Higher Education and Research
Outcome results
None listed