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Salbutamol Nebulization in Normal Saline versus Salbutamol Nebulization in Hypertonic Saline(3%) in Children with Acute Exacerbation of Asthma

Salbutamol nebulization in normal saline versus salbutamol nebulization in hypertonic saline(3%) in children with acute exacerbation of asthma

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055475
Enrollment
200
Registered
2023-07-21
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J455- Severe persistent asthma

Interventions

Intervention1: Salbutamol Nebulization in Normal Saline versus Salbutamol Nebulization in Hypertonic Saline (3%) in Children with Acute Asthma Exacerbation: Salbutamol Nebulization in Normal Saline ve

Sponsors

Dr Kapil Bhalla
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Children age 5-14 years diagnosed with acute asthma exacerbation consistent with moderate to severe severity according to Becker Asthma Severity score

Exclusion criteria

Exclusion criteria: Children with abnormal development of airway ,congenital respiratory disease Children with known history of heart ,liver ,neurological or kidney disease Children with evidence of pneumonia as per WHO ARI classification Children with history of tachyarrhythmia and bradyarrhythmia . Those children whose parents refuse to give consent to participial in study

Design outcomes

Primary

MeasureTime frame
To assess the clinical response when Salbutamol nebulization done in normal saline versus salbutamol nebulization done in hypertonic saline (3%) in children with acute asthma exacerbation which will be defined by Beckerâ??s Asthma Severity Score .Clinical improvement will be assessed by using Pediatrics Respiratory Asthma Score (PRAM)Timepoint: At 1 hour

Secondary

MeasureTime frame
To assess length of stay in hospital 2. To assess PICU admission in hospital.Timepoint: 6 hour

Countries

India

Contacts

Public ContactMohan Lal

PT B.D Sharma PGIMS ROHTAK

kapil_bhalla@yahoo.com9813743565

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026