Health Condition 1: J22- Unspecified acute lower respiratory infection
Conditions
Interventions
Intervention1: incremental PEEP for 25 minutes: Serial Positive end expiratory pressure from 5 to 10 and then to 15 is done and Lung ultrasound scores are measured along with abg. The duration of appl
Sponsors
None
Eligibility
Inclusion criteria
Inclusion criteria: 1) ARDS by Berlin definition 2) Pulmonary edema 3) Lung collapse 4) Lung consolidation
Exclusion criteria
Exclusion criteria: 1) Hemodynamic instability, with the use of norepinephrine >0.2 mcg/kg/min or an equivalent dose of other vasoactive agents (epinephrine >0.2 mcg/kg/min, dopamine >5 mcg/kg/min, vasopressin >0.01 units/min) 2) Decompensated heart failure 3) Raised intracranial pressure (ICP) 4) Presence of pneumothorax 5) Chronic obstructive pulmonary disease 6) Emphysematous lung 7) Patients on end-of-life care 8) Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| correlate recruitability between Lung USG & R/I ratioTimepoint: PEEP recruitment will be performed only once within 48 hours of ventilation | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation between delta aeration score & R/I ratio Correlation between Re-aeration score and R/I ratio Correlation between P/F ratio and delta aeration score Correlation between P/F ratio and reaeration score Correlation between P/F ratio and R/I ratio In patients who have spontaneous respiratory efforts only the following scores will be recorded Delta aeration score and P/F ratio Reaeration score and P/F ratio Timepoint: 5 min, 10 min, 25 mins | — |
Countries
India
Contacts
Public ContactDr Jose Chacko
Narayana Health City
Outcome results
None listed