None listed
Conditions
Interventions
Intervention1: Nil: Nil
Sponsors
Iom Bioworks Private Limited
Eligibility
Inclusion criteria
Inclusion criteria: Participant age between 40-80years. Participant BMI is between 18 to 29.9 kg/m2. Participant is self-reported healthy. Participant include male and female of equal ratio. Participant is willing to undergo lab investigations and provide stool sample for analysis at suggested timelines. Participant is willing to follow the suggestions made by the investigators for a duration of 4 weeks. Participants willing to come to study site in physical twice during the study. Participants should inform the investigators about any changes undertaken during the period of the study that deviates from inclusion and exclusion criteria.
Exclusion criteria
Exclusion criteria: Participant is on any strict diet like keto/fad/ vegan/ intermittent fasting etc. If the participant has used antibiotics, antifungals, anti-viral medication in the last 6 months. Participant on Antitubercular medications in the last 2 years. Participant on chemotherapy or received chemotherapy during the past 3 years. Participant having history of chronic, clinically significant with ongoing medication for systematic illness pertaining to GIT, liver, cardiovascular, hepatic , Pulmonary, renal ailments, and cancer as determined by medical history or physical examination. Any confirmed or suspected condition/state of immunosuppression or immunodeficiency (primary or acquired) including HIV infection. If the participant has taken large doses of commercially available probiotics for a long duration in the last 6 months. (in any form like tablet, powders, in which probiotics are primary component). Common dietary supplements like yogurt, buttermilk and other preparations made of them are not considered in this. Unstable dietary history as defined by major changes in diet during the previous month, where the subject has eliminated or significantly increased a major food group in the diet. If the participant has undergone treatment like induced vomiting (vamana), Induced emesis (Virechana) Medicated enema, procedures like douti, in the past 2 months. If the participant is on any long-term medications for chronic gut disease from AYUSH system (herb/ home remedies and herbal formulations for improving digestion and amapachana for short term are not considered in this). If the participant is on any kind of laxatives regularly in the past 6 months. Participant had covid -19 in the last 2 months Participant having uncontrolled diabetes (RBS > 200mg/dl and HbA1c >8%). Participant is having Hypertension Stage II or higher (Systolic >140mmof Hg and Diastolic >90). If the participant has undergone major surgery of GI tract with the exception of cholecystectomy and appendectomy, in the past five years. Any major bowel resection at any time. If the participant is hyperlipidaemia high risk group. Pregnant / lactating women. If the participant is alcoholic/ heavy drinker. If the participant is a chronic smoker. If the participant was diagnosed and treated for major psychiatric disorders in the last one year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Biomarkers and microbial signatures for health that can be used to assess and guide the health of elderly Timepoint: baseline and 4th week | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of microbiome patterns against the hallmarks of ageingTimepoint: Day 1 & at the end of the study after 4 weeks (day 30) following that. | — |
Countries
India
Contacts
Public ContactDr Pavithra N
The University of Trans-Disciplinary HealthSciences and Technology
Outcome results
None listed