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Application of nano-hydroxyapatite toothpaste to reduce sensitivity during tooth whitening procedure

Effect of pre- and post-operative application of nano-hydroxyapatite dentifrice on tooth sensitivity and color change following laser-assisted in-office vital bleaching-An observational study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055427
Enrollment
42
Registered
2023-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K037- Posteruptive color changes of dental hard tissues

Interventions

Intervention1: Post bleaching: Nano hydroxyapatite dentifrice 5gm once, for 4 minutes daily Intervention2: NIL: NIL Control Intervention1: Pre bleaching: Nano hydroxyapatite dentifrice 5gm once, for 4

Sponsors

SRM Dental College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged 18-30 years 2.Patients with good oral health and oral hygiene 3.Motivated patients 4.Patients with intact natural maxillary anterior teeth (Right canine to left canine) 5.Patients with a chief complaint of discolouration of maxillary anterior teeth 6.Patients belonging to ASA (American Society of Anaesthesiologists) Category I 7.Non-smokers

Exclusion criteria

Exclusion criteria: 1.Pregnant and lactating women 2.Periodontally compromised teeth with mobility 3.Teeth with gingival recession and /or non-carious cervical leisons 4.Patients known to be allergic to any of the ingredients in the bleaching agent used 5.Patients with visible cracks on the buccal surface of tooth 6.Patients with untreated tooth sensitivity 7.Patients undergoing orthodontic treatment 8.Patients with presence of severe internal discoloration (tetracycline stains, fluorosis, non-vital teeth) 9.Patients with presence of crowns, caries or restorations on the labial surfaces in maxillary anterior teeth 10.Teeth with congenital anomalies and surface defects 11.Patients who had previously undergone bleaching therapy

Design outcomes

Primary

MeasureTime frame
reduced tooth sensitivityTimepoint: immediate, 1hr, 24hrs, 48hrs

Secondary

MeasureTime frame
whitening of teethTimepoint: Immediate, 1 week, 1 month

Countries

India

Contacts

Public ContactDr S Mahalaxmi

SRM Institute of Science and Technology

vidhyas@srmist.edu.in9445563355

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026