A study where we will compare the healing effects of different aqueous-based vehicles used for mixing calcium hydroxide powder and placing it in the root canals during the inter-appointment period while treating patients with pulpal necrosis & symptomatic apical periodontitis.

Healing outcome of different aqueous based calcium hydroxide intracanal medicament in patients with pulpal necrosis and symptomatic apical periodontitis: a randomized controlled trial. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055398

Enrollment

Registered

2023-07-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Group 2: 25 patients with intracanal medicament as Calcium hydroxide mixed with 2 percent lidocaine hydrochloride solution for 7 days Intervention2: Group 3: 25 patients with intraca

Eligibility

Inclusion criteria

Inclusion criteria: Mandibular molar teeth diagnosed with symptomatic apical periodontitis and pulpal necrosis, Teeth with mature apices

Exclusion criteria

Exclusion criteria: Patients with periodontal disease or systemic disorders, patients taking steroids, pregnant patients, or patients with a history of antibiotic intake in the preceding month, Patients with a history of allergy to any of the components of local anesthesia, chlorhexidine, EDTA, or sodium hypochlorite, Teeth with previous RCT, Severely damaged or mutilated teeth, Patients not willing to participate in the study and did not sign the consent form.

Design outcomes

Primary

Measure	Time frame
Differences were expected in apical bone density by comparing the pre-operative PAI scoring & post-operative PAI scoring.Timepoint: Periapical healing at 3months 6 months 9 months & 12 months	—

Secondary

Measure	Time frame
To compare the difference in apical bone density by comparing the pre-operative PAI scoring & post-operative PAI scoring.Timepoint: Periapical healing at 3months 6 months 9 months & 12 months	—

Countries

India

Contacts

Public ContactALPA GUPTA

MANAV RACHNA DENTAL COLLEGE

alpagupta2008@gmail.com9050312010

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026