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Gene Polymoprhism of a novel Biomarker in Symptomatic Irreversible Pulpitis and Chronic Apical Periodontitis

Association of NLRP3 single nucleotide  polymorphism in gingival crevicular fluid of patients diagnosed with Symptomatic Irreversible Pulpitis & Chronic Apical Periodontitis in a section of the North Indian population â?? A case-control study â?? - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055397
Enrollment
48
Registered
2023-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K045- Chronic apical periodontitis Health Condition 2: K040- Pulpitis

Interventions

None listed

Sponsors

Saumya Verma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with symptomatic irreversible pulpitis according to AAE guidelines. Patients diagnosed with chronic apical periodontitis according to AAE guidelines Patients with no relevant history and systemic diseases.

Exclusion criteria

Exclusion criteria: Patients with multiple carious teeth. Patients with any systemic condition.

Design outcomes

Primary

MeasureTime frame
Single nucleotide polymorphism of NLRP3 gene is sought to be detectedTimepoint: 1 year 6 months—

Secondary

MeasureTime frame
Assessment of levels of NLRP3 levels in SIP patients, CAP patients & healthy controls.Timepoint: 1 year 6 months—

Countries

India

Contacts

Public ContactDax Abraham

Manav Rachna Dental College

daxabraham.mrdc@mrei.ac.in9910433111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026