Effect of Calcium Hydroxide as an intracanal medicament with aqueous and viscous based vehicles in patients with pulpal necrosis and symptomatic apical periodontitis on post operative pain and healing outcome

Comparative Evaluation of Calcium Hydroxide as an Intracanal Medicament with Aqueous and Viscous Based Vehicles in Patients with Pulpal Necrosis and Symptomatic Apical Periodontitis: Impact on Postoperative Pain and Healing Outcome - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055396

Enrollment

Registered

2023-07-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K044- Acute apical periodontitis of pulpal origin

Interventions

Intervention1: Saline group: 25 patients with calcium hydroxide and 0.2% saline as intracanal medicament for 7 days Control Intervention1: Propylene Glycol group : 25 patients with caclium hydroxide a

Eligibility

Inclusion criteria

Inclusion criteria: Mandibular molars diagnosed with Pulp necrosis and Symptomatic apical periodontitis and Teeth with mature apices

Exclusion criteria

Exclusion criteria: Patients who had taken analgesics or anti-inflammatory drugs within the last 12 hours, Teeth with calcified canals and aberrant root canal morphology, Pregnant or lactating patients, Patients with history of allergy to any of the components of local anesthesia, Teeth with previous RCT, Severely damaged or mutilated teeth, Patients with any systemic diseases,

Design outcomes

Primary

Measure	Time frame
Differences expected in the level of post-operative pain & healingTimepoint: post operative pain will be evaluated at 6, 24,48 & 72 hours Periapical healing will be evaluated at 3,6,9 & 12 months	—

Secondary

Measure	Time frame
Differences expected in the level of post operative pain & healing in patients of pulpal necrosis & symptomatic apical periodontitis after placing calcium hydroxide with aqueous & viscous vehiclesTimepoint: Post operative pain will be evaluated at 6, 24, 48 &72 hours Periapical healing will be evalauted at 3,6,9 & 12 months by comparing the pre operative & post operative Periapical Index(PAI) Score	—

Measure

Time frame

Differences expected in the level of post operative pain & healing in patients of pulpal necrosis & symptomatic apical periodontitis after placing calcium hydroxide with aqueous & viscous vehiclesTimepoint: Post operative pain will be evaluated at 6, 24, 48 &72 hours Periapical healing will be evalauted at 3,6,9 & 12 months by comparing the pre operative & post operative Periapical Index(PAI) Score

—

Countries

India

Contacts

Public ContactDax Abraham

Manav Rachna Dental College

daxabraham.mrdc@mrei.ac.in9910433111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026