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COMPARING THE EFFECT OF PLAIN ROPIVACAINE 0.375% AND ROPIVACAINE WITH NALBUPHINE FOR ADDUCTOR CANAL BLOCK AS A MODE OF POSTOPERATIVE ANALGESIA IN UNILATERAL TOTAL KNEE REPLACEMENT

“ADDUCTOR CANAL BLOCK FOR POSTOPERATIVE ANALGESIA AFTER SIMULTANEOUS UNILATERAL TOTAL KNEE REPLACEMENT; A COMPARATIVE EVALUATION OF NALBUPHINE AS AN ADJUVANT TO ROPIVACAINE ?

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055386
Enrollment
30
Registered
2023-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj.Ropivacaine: 19ml of 0.375% Inj. Ropivacaine with 1ml of Normal Saline In Adductor Canal Block as Single Dose Control Intervention1: Inj.Ropivacaine with Inj.Nalbuphine: 19ml of 0.3

Sponsors

Department of Anaesthesiology
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patient scheduled for elective Total knee replacement surgery with American society of anaesthsiologist (ASA) physical status grade 1 and 2 2.patient willing to give informed consent 3.patient with Age between 35 to 65 years

Exclusion criteria

Exclusion criteria: 1.patient with severe chronic obstructive pulmonary disease 2.Coagulation disorders 3.known allergy to any of the study drugs 4.Local infection 5.focal neurological deficit in lower limb

Design outcomes

Primary

MeasureTime frame
To study the duration of postoperative analgesia after Adductor Canal Block performed.Timepoint: In the Immediate Postoperative period

Secondary

MeasureTime frame
Time of ambulation in two groups Haemodynamic stability Total analgesic requirement for next 12hours Any side effects in postoperative Day 0 and 1 Timepoint: Post op Day 0 and 1

Countries

India

Contacts

Public ContactDrSHANKRAPPA LAMANI

Chamarajanagar institute of medical sciences

darshanms_jss@yahoo.com9741376797

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026