Role of regional block (Infraorbital nerve block) in conjunction with general anaesthesia for intra-operative haemodynamic management and post-operative pain control in patients undergoing Pituitary Surgery.

ROLE OF BILATERAL INFRAORBITAL NERVE BLOCK AS AN ADJUVANT TO GENERAL ANAESTHESIA IN PATIENTS UNDERGOING TRANS-NASAL TRANS-SPHENOIDAL PITUITARY SURGERY: A PROSPECTIVE RANDOMIZED CONTROLLED STUDY - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055385

Enrollment

Registered

2023-07-20

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Infraorbital nerve block: Patients will receive bilateral infraorbital nerve block using 0.75% Ropivacaine 4mL (2mL on each side) along with general anaesthesia in one group and other g

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group 18-65 years Patients belonging to ASA-I/II category Patients planned to undergo elective trans-nasal trans-sphenoidal pituitary surgery

Exclusion criteria

Exclusion criteria: Known allergy to study drug Refusal to participate in study Inability to comprehend or adhere to study protocol GCS Pregnancy Faciomaxillary deformities BMI >40kg/m2 Known allergy to NSAIDs

Design outcomes

Primary

Measure	Time frame
Time to first rescue analgesiaTimepoint: Visual analogue scale for pain assessment at the time of extubation, 1st hour, 4th hour, 8th hour, 12th hour and 24th hour postoperatively	—

Secondary

Measure	Time frame
To compare intra-operative haemodynamic fluctuations between the two groups To compare emergence from anaesthesia between the two groups To compare post-operative analgesia using VAS scores between the two groups To compare post-operative analgesic requirement for 24 hours after surgery between the two groupsTimepoint: Assessment of Blood pressure & heart rate at 1 min & 5 min of induction, at the time of infraorbital nerve block, 5 min after block & every 10 min henceforth till 60 min Assessment of Ramsay agitation sedation score 1 min after extubation, 10 min, 30 min after extubation, 1st, 2nd & 4th hour after extubation Assessment of time to first rescue analgesia if VAS score is more than or equal to 4	—

Measure

Time frame

To compare intra-operative haemodynamic fluctuations between the two groups To compare emergence from anaesthesia between the two groups To compare post-operative analgesia using VAS scores between the two groups To compare post-operative analgesic requirement for 24 hours after surgery between the two groupsTimepoint: Assessment of Blood pressure & heart rate at 1 min & 5 min of induction, at the time of infraorbital nerve block, 5 min after block & every 10 min henceforth till 60 min Assessment of Ramsay agitation sedation score 1 min after extubation, 10 min, 30 min after extubation, 1st, 2nd & 4th hour after extubation Assessment of time to first rescue analgesia if VAS score is more than or equal to 4

—

Countries

India

Contacts

Public ContactKanika Gupta

Paras Hospital

docmmg@gmail.com9871174766

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026