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Effects of two medication on breathing tube insertion: Dexmeditomedine vs fentanyl

Evaluation of Intubating Conditions and Haemodynamic Response With DEXMEDITOMIDINE vs FENTANYL When Used as Premedicationâ??

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055341
Enrollment
96
Registered
2023-07-19
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: R688- Other general symptoms and signs

Interventions

Intervention1: DEXMEDITOMIDINE-0.5µg/kg vs FENTANYL-2µg/kg: DEXMEDITOMIDINE-0.5µg/kg over 10 min and FENTANYL-2µg/kg over 10min as premedication for evaluating hemodynamic response for intubati

Sponsors

Topiwala National Medical college and B Y L Nair hospital
Lead Sponsor
Dr Pradeep Chavan
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1)Adults aged between 18 to 60 years. 2)Weight between 50 to 70 kgs 3)ASA 1 and ASA 2 patients.

Exclusion criteria

Exclusion criteria: 1)ASA 3 and ASA 4 patients. 2) with uncontrolled Hypertension, DM, COPD. 3)Severe cardiac, cerebrovascular, respiratory disease. 4)Hepatic & renal dysfunction. 5)Anticipated difficult intubation (Mallampatti class 3 and 4). 6)Patient refusal to participate in study. 7Allergy to drugs

Design outcomes

Primary

MeasureTime frame
HEART RATE, SYSTOLIC BLOOD PRESSURE, DIASTOLIC BLOOD PRESSURE,MEAN ARTERIAL PRESSURETimepoint: Heart Rate, Systolic Blood Pressure, Diastolic Blood Pressure,Mean Arterial Pressure will be assessed preoperatively,post study drug administration,post intubation,1min after intubation,5min after intubation,10min after intubation

Secondary

MeasureTime frame
Consumption of etomidate at time of intubationTimepoint: Till loss of eyelash response

Countries

India

Contacts

Public ContactDr_Pradeep Chavan

Topiwala National Medical college and B Y L Nair Hospital

drmangeshg166@gmail.com9223233165

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026