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Injectable 2% Hyaluronic acid vs i-PRF for reconstruction of lost interdental papilla.

Comparative evaluation of 2% injectable Hyaluronic acid versus i-PRF for reconstruction of lost interdental papilla : A Randomized Clinical Trial. - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055307
Enrollment
14
Registered
2023-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K055- Other periodontal diseases Health Condition 2: K055- Other periodontal diseases

Interventions

Intervention1: 2% Hyaluronic Acid Injection: Oral prophylaxis will be done. The area will be anaesthetised with a local infiltration Lignocaine hydrochloride and 2% adrenaline 1in 80,000 injection (XI

Sponsors

Mohammed Ashif
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy participants. 2.Class I or class II papilla according to Nordland and Tarnowâ??s Classification system for loss of papillary height. 3.Loe and Silness gingival index less than or equal to 1.

Exclusion criteria

Exclusion criteria: 1. Participants using any form of tobacco. 2. Pregnant or lactating females. 3. Participants who are already on anti-inflammatory or anti-bacterial drugs. 4. Participants using a drug which has influence in gingival growth. 5. Participants with midline diastema / loss of proximal contact. 6. Participants with untreated maxillary anterior caries, prosthesis and orthodontic appliances.

Design outcomes

Secondary

MeasureTime frame
To compare the effectiveness of 2% HA and i-PRF in the reconstruction of lost interdental papilla.Timepoint: At baseline, endo of 1st and 3rd month;To evaluate the effectiveness of injectable platelet-rich fibrin (i-PRF) in the reconstruction of lost interdental papilla.Timepoint: At baseline, end of 1st and 3rd month

Primary

MeasureTime frame
To assess the amount of papillary fill in the maxillary anterior region in the following groups of participants at the end of 3rd month, Group 1 with 2% Hyaluronic Acid Group 2 with i-PRF.Timepoint: Baseline, at the end of 1 month and at the end of 3rd month.

Countries

India

Contacts

Public ContactMOHAMMED ASHIF K

Yenepoya Dental College

drvinitaboloor@gmail.com9845114652

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026