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Comparison of left ventricular ejection fraction obtained by using 3D echo modality called 3D EPSS with currently practiced methods of echo 2D EPSS, and 2D simpsons and 3D volumetric methods.

Comparison of left ventricular ejection fraction obtained by 2D mitral E point septal separation and 3D mitral E point septal separation linear and area methods with that of 2D and 3D volumetric methods using transesophageal echocardiography. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055283
Enrollment
50
Registered
2023-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery

Interventions

Intervention1: NIL: NIL

Sponsors

Sree Chitra Tirunal Institute for Medical Sciences and Technology Trivandrum
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adults above 18 years of age, in sinus rhythm, admitted with CAD for elective CABG surgery will be included in the study.

Exclusion criteria

Exclusion criteria: 1. Emergency surgeries 2. Redo surgeries 3. Patients not willing to participate in study 4. More than mild AR, MR or TR 5. Patients with Mitral valve pathology causing restricted or increased mobility of leaflets 6. Patients receiving preoperative inotropes 7. Patients with poor echo differentiation of endocardial borders 8. Patient with arrhythmias. 9. Contraindication to TEE probe placement like esophageal strictures, esophageal varices, esophageal tumors, gastric ulcer, previous esophagectomy, esophageal diverticulum, tracheoesophageal fistula, previous bariatric surgery, hiatus hernia, large descending thoracic aortic aneurysm, unilateral vocal cord paralysis, esophageal varices, post-radiation therapy

Design outcomes

Primary

MeasureTime frame
1. Comparison of 2D mitral EPSS-based LVEF & 3D mitral EPSS-based LVEF with 2D LVEF measured from modified Simpson’s formula in patients with normal LV systolic function (LVEF more than 52% in men & 54% in women) & their correlation with LVEF obtained by 3DE volumetric assessment as a reference method. 2. Correlation of 3D mitral EPSS area with 2DE modified Simpson’s LVEF & 3DE LVEF in patients with good LV & deranged LV function. We also would try to derive a formula to calculate LVEF using 3D EPSS area. Timepoint: Pre CPB initiation

Secondary

MeasureTime frame
1. Comparison of LVEF obtained by 2D & 3D mitral EPSS, modified Simpson’s formula and their correlation with LVEF obtained by 3DE volumetric assessment as a reference method. i.) in patients with deranged LV systolic function ii.) in patients without dilated LV iii.) formula in patients with dilated LV 2. Correlation of 3D mitral EPSS area with measured LVEF in patients with dilated LV and non-dilated LV. We also would try to derive a formula to calculate LVEF using 3D EPSS area. 3. To assess the correlation between 3D EPSS on postoperative outcome parameters 4. To ascertain the intraobserver variability and interobserver variability.Timepoint: Pre CPB initiation Post extubation Pre discharge from ICU

Countries

India

Contacts

Public ContactV Krishna Narayanan Nayanar

Sree Chitra Tirunal Institute for Medical Sciences and Technology

shri@sctimst.ac.in9446304043

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026