Health Condition 1: I251- Atherosclerotic heart disease of native coronary artery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: All adults above 18 years of age, in sinus rhythm, admitted with CAD for elective CABG surgery will be included in the study.
Exclusion criteria
Exclusion criteria: 1. Emergency surgeries 2. Redo surgeries 3. Patients not willing to participate in study 4. More than mild AR, MR or TR 5. Patients with Mitral valve pathology causing restricted or increased mobility of leaflets 6. Patients receiving preoperative inotropes 7. Patients with poor echo differentiation of endocardial borders 8. Patient with arrhythmias. 9. Contraindication to TEE probe placement like esophageal strictures, esophageal varices, esophageal tumors, gastric ulcer, previous esophagectomy, esophageal diverticulum, tracheoesophageal fistula, previous bariatric surgery, hiatus hernia, large descending thoracic aortic aneurysm, unilateral vocal cord paralysis, esophageal varices, post-radiation therapy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Comparison of 2D mitral EPSS-based LVEF & 3D mitral EPSS-based LVEF with 2D LVEF measured from modified Simpson’s formula in patients with normal LV systolic function (LVEF more than 52% in men & 54% in women) & their correlation with LVEF obtained by 3DE volumetric assessment as a reference method. 2. Correlation of 3D mitral EPSS area with 2DE modified Simpson’s LVEF & 3DE LVEF in patients with good LV & deranged LV function. We also would try to derive a formula to calculate LVEF using 3D EPSS area. Timepoint: Pre CPB initiation | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Comparison of LVEF obtained by 2D & 3D mitral EPSS, modified Simpson’s formula and their correlation with LVEF obtained by 3DE volumetric assessment as a reference method. i.) in patients with deranged LV systolic function ii.) in patients without dilated LV iii.) formula in patients with dilated LV 2. Correlation of 3D mitral EPSS area with measured LVEF in patients with dilated LV and non-dilated LV. We also would try to derive a formula to calculate LVEF using 3D EPSS area. 3. To assess the correlation between 3D EPSS on postoperative outcome parameters 4. To ascertain the intraobserver variability and interobserver variability.Timepoint: Pre CPB initiation Post extubation Pre discharge from ICU | — |
Countries
India
Contacts
Sree Chitra Tirunal Institute for Medical Sciences and Technology