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Measuring different markers of labor pain in pregnant patients and its relation

Correlation Between Noradrenaline, Serotonin, GABA, and Glycine in Cerebrospinal fluid during labor pain undergoing cesarean section: A preliminary study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055282
Enrollment
100
Registered
2023-07-17
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O82- Encounter for cesarean delivery without indication

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil

Sponsors

AIIMS RESEARCH SECTION NEW DELHI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Singleton pregnancy 2. Term pregnancy 3. Elective and emergency cesarean section

Exclusion criteria

Exclusion criteria: 1. Complicated pregnancy (e.g, Eclampsia, placental abruption, uterine abruption) 2. Contraindication to spinal anesthesia 3. H/o of Chronic Pain and neuropathic pain 4. H/o Substance use that has an effect on Central nervous system 5. Already receiving labor epidural 6. H/o Psychiatric illness 5. H/o of any neurological disease

Design outcomes

Primary

MeasureTime frame
To evaluate the CSF concentrations of noradrenaline, serotonin, GABA & glycine between pregnant women with labor pain & those without labor painTimepoint: After spinal anaesthesia—

Secondary

MeasureTime frame
To assess the correlation between each neurotransmitter & pain intensity in the Labour pain group To assess the blood level above neurotransmitter between pregnant women with labor pain & those without labor pain & its correlation with CSF value To evaluate the correlation among the four different neurotransmitters. Timepoint: After spinal anaesthesia—

Countries

India

Contacts

Public ContactYudhyavir Singh

AIIMS

yudhyavir@gmail.com09811140057

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026