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Eradication of bacteria from root canals using nanoparticle based photodisinfection

Evaluation of antibacterial efficacy in the elimination of endodontic microflora by addition of silver nanoparticles and proton pump inhibitors to traditional photodynamic therapy: An invivo study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055249
Enrollment
52
Registered
2023-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: K041- Necrosis of pulp

Interventions

Intervention1: silver nanoparticles, proton pump inhibitor-verapamil, photoactivated disinfection: silver nanoparticles 50ppm,curcumin 100microlitre,verapamil 0.49mg, root canal irrigation each soluti

Sponsors

Garlapati Mounica
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Carious nonvital teeth. 2) Patients with no systemic disease and with no history of any antibiotics at the time of intervention

Exclusion criteria

Exclusion criteria: 1) Teeth that are grossly decayed with more than two walls missing. 2) Teeth with radiographic evidence of calcification. 3) Teeth with immature apices. 4) Patients with chronic periodontal disease

Design outcomes

Primary

MeasureTime frame
evaluate antibacterial efficacy of nanoparticle & proton pump inhibitor based photodynamic disinfection in root canal system compared to sodium hypochloriteTimepoint: 8weeks—

Secondary

MeasureTime frame
not applicableTimepoint: not applicable—

Countries

India

Contacts

Public ContactDr B Indira priyadarshini

St joseph dental college

indupriya2608@gmail.com9490764770

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026