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Effects of Sedentary Lifestyle on Brain Health & Cognitive Function in Hypertensive and Non-Hypertensive Adults

Differences in Structural Brain Network & Cognitive Functions between Sedentary Hypertensive and Non Hypertensive Adults - NIL

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2023/07/055243
Enrollment
154
Registered
2023-07-14
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

None listed

Sponsors

KMC Manipal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Hypertensive Non diabetic No history stroke or other cerebrovascular diseases No history of cardiovascular or other metabolic disorders

Exclusion criteria

Exclusion criteria: Age: below 18 and above 60 History of hypertension or under any anti hypertensive drugs History of diabetes, cerebrovascular or metabolic diseases

Design outcomes

Primary

MeasureTime frame
Structural brain integrity The MRI sequences â?? DTI and ASL will assess the mean diffusivity (MD), fractional anisotropy (FA) , Total Blood Volume (TBV) and Mean Transit Time (MTT) using the Brain MRI study Timepoint: 6hr after the MRI scan

Secondary

MeasureTime frame
To compare the white matter integrity & degeneration in sedentary individuals with different stages of hypertension To compare the volume of different regions of brain in sedentary individuals with different stages of hypertension To compare the structural brain network changes with the cognitive changes in different stages of hypertension To compare the structural brain network changes in hypertensive & non hypertensive adults Timepoint: 1hr prior to MRI scan with 1hr of minimum sitting time

Countries

India

Contacts

Public ContactSneha Ravichandran

Manipal College of Health Professionals, Manipal Academy of Higher Education

sneha.ravichandran@learner.manipal.edu8660837331

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026