Health Condition 1: I10- Essential (primary) hypertension
Conditions
Interventions
None listed
Sponsors
KMC Manipal
Eligibility
Inclusion criteria
Inclusion criteria: Hypertensive Non diabetic No history stroke or other cerebrovascular diseases No history of cardiovascular or other metabolic disorders
Exclusion criteria
Exclusion criteria: Age: below 18 and above 60 History of hypertension or under any anti hypertensive drugs History of diabetes, cerebrovascular or metabolic diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Structural brain integrity The MRI sequences â?? DTI and ASL will assess the mean diffusivity (MD), fractional anisotropy (FA) , Total Blood Volume (TBV) and Mean Transit Time (MTT) using the Brain MRI study Timepoint: 6hr after the MRI scan | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the white matter integrity & degeneration in sedentary individuals with different stages of hypertension To compare the volume of different regions of brain in sedentary individuals with different stages of hypertension To compare the structural brain network changes with the cognitive changes in different stages of hypertension To compare the structural brain network changes in hypertensive & non hypertensive adults Timepoint: 1hr prior to MRI scan with 1hr of minimum sitting time | — |
Countries
India
Contacts
Public ContactSneha Ravichandran
Manipal College of Health Professionals, Manipal Academy of Higher Education
Outcome results
None listed