Dexmeditomidine vs buprenorphine as an additive to bupivacaine in Spinal anaesthesia

Comparison of intrathecal dexmedetomidine with buprenorphine as an adjuvant to hyperbaric bupivacaine in infraumbilical surgeries - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055167

Enrollment

120

Registered

2023-07-13

Start date

Unknown

Completion date

Unknown

Last updated

2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: comparison of intrathecical dexmedetomidine with buprenorphine as an adjuvant to hyperbaric bupivacaine in infraumbilical surgeries: Aims and objective of study: To evaluate and compare

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I and ASA II participants. 2. Patients undergoing orthopaedic lower limb surgeries. 3. Patients undergoing lower umbilical general surgeries. 4. Women undergoing gynaecological surgeries. 5. Age-18-60 years. 6.weight-40kg to 80kg. 7.Height-150 cm and above.

Exclusion criteria

Exclusion criteria: 1.Patientâ??s refusal . 2.Patients with contraindication for specified drugs. 3.Obesity (BMI >30). 4.Pregnant patients. 5.Infection at the site of injection (spinal). 6.Coagulopathy or any other bleeding diasthesis. 7.Severe hypovolemia. 8.Increased intracranial pressure. 9.Structural and functional cardiac abnormalities. 10.Severe spinal deformity.

Design outcomes

Primary

Measure	Time frame
To evaluate & compare the following factors in two groups-intrathecal dexmedetomidine & intrathecal buprenorphine as an adjuvant to hyperbaric bupivacaine in infraumbilical surgeries with respect to: 1. Sensory & motor blockade -onset & duration. Timepoint: Time at which intrathecal drug is administered is T0, followed by T1 at 1min,T2 at 3 min,T3 at 5 min interval......till intraoperative period followed by time required for regaining of sensory and motor sensation in postoperative period.	—

Measure

Time frame

To evaluate & compare the following factors in two groups-intrathecal dexmedetomidine & intrathecal buprenorphine as an adjuvant to hyperbaric bupivacaine in infraumbilical surgeries with respect to: 1. Sensory & motor blockade -onset & duration. Timepoint: Time at which intrathecal drug is administered is T0, followed by T1 at 1min,T2 at 3 min,T3 at 5 min interval......till intraoperative period followed by time required for regaining of sensory and motor sensation in postoperative period.

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Secondary

Measure	Time frame
Duration of analgesiaTimepoint: perioperative to postoperative period	—

Countries

India

Contacts

Public ContactDR ABHIJIT DAS

Silchar Medical College and Hospital

adasdr14@gmail.com9401000010

Outcome results