To see the effect of low dose Phenylephrine infusion for prevention of shivering in patients undergoing elective lower segment Cesarean section - A Prospective Randomized Double Blinded Controlled Study

Efficacy of low dose Phenylephrine infusion for prevention of shivering in patients undergoing elective lower segment Cesarean section - A Prospective Randomized Double Blinded Controlled Study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055153

Enrollment

112

Registered

2023-07-13

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium

Interventions

Intervention1: Low dose Phenylephrine infusion in prevention of shivering in elective lower segment cesarean section: Low dose of Phenylephrine infusion is given at a rate of 0.25mcgs/kg/min is given

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective lower segment caesarean section 2. ASA class II 3. Age >18 years

Exclusion criteria

Exclusion criteria: 1. Patients with fever >37 degree Celsius 2. Hypertensive disorders 3. Cardiac diseases 4. Antepartum hemorrhage 5. Known allergy to drugs used in study 6. Intraoperative blood loss more than 1000ml 7. Need for RBC transfusion

Design outcomes

Primary

Measure	Time frame
1)Incidence of shivering 2)Grade of shivering 3)Need for rescue medications Timepoint: 1)Incidence of shivering is assessed from 1 minute after giving spinal anesthesia till the entire cesarean section and estimated at baseline 2)Grade of shivering is assessed from 1 minute after giving spinal anesthesia till the entire Cesarean section estimated at baseline 3)Need for rescue medications is assessed from 1 minute after giving spinal anesthesia till the end of Cesarean section	—

Measure

Time frame

1)Incidence of shivering 2)Grade of shivering 3)Need for rescue medications Timepoint: 1)Incidence of shivering is assessed from 1 minute after giving spinal anesthesia till the entire cesarean section and estimated at baseline 2)Grade of shivering is assessed from 1 minute after giving spinal anesthesia till the entire Cesarean section estimated at baseline 3)Need for rescue medications is assessed from 1 minute after giving spinal anesthesia till the end of Cesarean section

—

Secondary

Measure	Time frame
1)Temperature 2)Mean arterial pressure 3)Systolic & diastolic pressure Timepoint: 1)Temperature at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit 2)Mean arterial pressure at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit 3)Systolic & diastolic pressure at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit	—

Measure

Time frame

1)Temperature 2)Mean arterial pressure 3)Systolic & diastolic pressure Timepoint: 1)Temperature at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit 2)Mean arterial pressure at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit 3)Systolic & diastolic pressure at baseline & 1 minute after giving spinal anesthesia till the end of procedure & in Post Anesthetic care unit

—

Countries

India

Contacts

Public ContactAkilandeshwari

Sri Ramachandra Institute Of Higher Education And Research

akilaanes@gmail.com9840636238

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026