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Use of biologics like Platelet rich plasma in osteoarthritis of knee for cartilage regeneration

A study on Osteoarthritis of knee evaluating the effects of Biologics with Bio-mechanical correction for regeneration of cartilage.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055142
Enrollment
30
Registered
2023-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue Health Condition 2: M171- Unilateral primary osteoarthritisof knee

Interventions

Intervention1: PRP and proximal fibular osteotomy: The patient will be managed with proximal fibular osteotomy along with PRP infiltration into the knee joint of the operated side and the clinical out

Sponsors

JAWAHARLAL NEHRU MEDICAL COLLEGE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1- Patients OA knee - Grade II and III 2- Radiological evidence of medial compartment involvement. 3- Primary OA knee patients. 4- Patients who are willing to take part in study after informed consent

Exclusion criteria

Exclusion criteria: 1-Post traumatic knee stifness 2-History of infective joint disease. 3-Patients with history of previous surgeries of knee. 4-Co-morbid/pathology of ipsilateral hip/foot joint pathology 5-Any other defect of ipsilateral limb like shortening etc.

Design outcomes

Primary

MeasureTime frame
Biomechanical correction with biologics (PRP) can lead to cartilage regenerationTimepoint: at 0 , 3 , 12 , 24 weeks and 9 months

Secondary

MeasureTime frame
Correction of varus deformityTimepoint: Correction of varus deformity at 0, 6 , 12 , 24 weeks and 6 and 9 months

Countries

India

Contacts

Public ContactDr Sandeep Shrivastava

DATTA MEGHE INSTITUTE OF HIGHER EDUCATION AND RESEARCH

drsandeepshrivastava@gmail.com9975170898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026