Health Condition 1: R888- Abnormal findings in other body fluids and substances
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
Dr Pooja Sinha
Eligibility
Inclusion criteria
Inclusion criteria: Patients above 18 years of age with tobacco habits will be included in the study and will be divided into 2 groups: Group I: Control group of 74 healthy individuals with tobacco habit Group II: Case group of 74 OPMD patients with tobacco habits
Exclusion criteria
Exclusion criteria: Patients with alcohol habit Pregnant and lactating women. Subjects with previous treatment for OPMDs. Subjects with any collagen diseases or immune mediated disorders. Subjects with history of head and neck tumors, breast cancer and gastric cancer. Subjects with prior neoplastic surgeries and cancer metastases. Other diseases such as HIV, Hepatitis, infectious diseases, coronary artery disease, cardiovascular disorders where alteration in salivary biomarkers level can be present.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A. Alternative Hypothesis In-silico analysis is a recent method and have significant approach in identifying salivary mRNA based biomarker in OPMD. Timepoint: 2 years | — |
Secondary
| Measure | Time frame |
|---|---|
| Pre-clinical validation of salivary mRNA biomarkers among patients with tobacco habit and oral potentially malignant patientsTimepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr Pooja Sinha
Sri Rajiv Gandhi College of Dental Sciences, Bangalore
Outcome results
None listed