A clinical trial to study the effect of Noni fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects

Evaluation of Morinda citrifolia (Noni) fruit extract as a bone regenerative material in the treatment of periodontal intrabony osseous defects:A split mouth clinical and radiographic study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055134

Enrollment

Registered

2023-07-12

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Morinda Citrifolia (Noni) Fruit Extract: Morinda citrifolia has antiinflammatory,wound healing, and periodontal tissue regeneration activities and its regenrative propertities will be e

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients ready to give informed consent. 2.Age group: 30-55 years of either sex. 3.Patients with no systemic disease. 4.Patients with chronic periodontitis. 5.The patients should have an ability to maintain good oral hygiene. 6.The patients must give an informed consent for the surgical procedure. 7.Patient with bilateral periodontal pockets of =5 mm and radiographic evidence of vertical bone loss.

Exclusion criteria

Exclusion criteria: 1.The patients showing unacceptable and non-compliant oral hygiene during presurgical (Phase I) period. 2.Any Systemic illness known to affect the outcome of periodontal therapy. 3.Allergic to medications. 4.Pregnant and lactating women. 5.Use of tobacco/smoking in any form. 6.Patients with orthodontic malformed teeth. 7.Handicapped and mentally retarded patients

Design outcomes

Primary

Measure	Time frame
Effectiveness of Morinda citrifolia (noni) fruit extract under parameters like Plaque Index,Gingival index,Probing pocket depth,Clinical attachment level,Radiographic assessment of bone gainTimepoint: 6 months	—

Secondary

Measure	Time frame
Effectiveness of Morinda citrifolia (noni)fruit extract under secondary parameters of age & genderTimepoint: 6 months	—

Countries

India

Contacts

Public ContactDr Shivani Sachdeva

Pravara Institute of Medical Sciences Loni

drmaniamit@gmail.com9730548805

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026