Management of low blood pressure during surgery with drugs like adrenaline or noradrenaline to improve blood pressure in patients undergoing vascular (blood vessels)surgery and follow up of patients for complications in postoperative period

Intraoperative hypotension management with adrenaline infusion vs noradrenaline infusion and complications after vascular surgery-A pilot, pragmatic, randomized control trial - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2023/07/055132

Enrollment

100

Registered

2023-07-12

Start date

Unknown

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I779- Disorder of arteries and arterioles, unspecified

Interventions

Intervention1: Adrenaline arm: infusion of adrenaline followed by noradrenaline at dose of 0.02mcg per kg if required in event of mean arterial pressure less than 80 mm Hg and dose increased upto 0.1m

Eligibility

Inclusion criteria

Inclusion criteria: 1.Age 18-80 years, 2.American Society of Anesthesiologists (ASA) physical status I, II and III , 3.Patient undergoing elective vascular surgery

Exclusion criteria

Exclusion criteria: 1. Patient already receiving mechanical ventilation 2.Patient already receiving inotrope 3.Poorly controlled hypertension 4. Planned reoperation within 3 months 5.Preoperative immobility or inability to walk unaided 6.Pregnancy

Design outcomes

Primary

Measure	Time frame
Effect of intraoperative hypotension management with adrenaline vs noradrenaline on composite of death, major cardio vascular complications, major neurological complications, renal complications, pulmonary complications and gastro intestinal complicationsTimepoint: 7th day and 90th day postoperatively	—

Secondary

Measure	Time frame
Effect of intraoperative hypotension management with adrenaline vs noradrenaline on organ specific complication, Effect of intraoperative hypotension management with adrenaline vs noradrenaline on quality of life ,Effect of intraoperative hypotension management with adrenaline vs noradrenaline on length of hospital & ICU stay Timepoint: 1st postop day & 7th day & 90th day postoperatively	—

Countries

India

Contacts

Public ContactDr Deepika N V

Jawaharlal Institute of Postgraduate Medical Education and Research

drajaykjha@rediffmail.com09868477642

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Aug 9, 2026