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Multimodal Intervention Trial to reduce dementia and disability in india

Multimodal Intervention Trial for the Prevention of Dementia - A Pilot Study - NILL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055130
Enrollment
120
Registered
2023-07-12
Start date
Unknown
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F068- Other specified mental disorders due to known physiological condition

Interventions

Intervention1: Multimodal Intervention: The intervention includes targeting the multiple domains such as Dietary modifications, Physical activity, Mindfulness based contemplative practices, Cognitive

Sponsors

TATA EDUCATION TRUST
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants of either gender who are above 55 years of age 2. Clinical Dementia Rating score of 0 or 0.5

Exclusion criteria

Exclusion criteria: 1. Substantial cognitive decline, CDR > 0.5 2. Significant cardiopulmonary diseases. 3. History of major heart surgery (i.e., valve replacement, bypass surgery, angioplasty) in the past 6 months. 4. Malignancy. 5. End stage of renal disease requiring dialysis. 6. History of fracture, joint replacement, or spinal surgery in the last 6 months. 7. History of alcohol or substance dependence in last 12 months 8. Parkinson’s disease 9. Neurological & psychological illness

Design outcomes

Primary

MeasureTime frame
COGNITO HMSE CDR ACE III (R) Feasibility MeasuresTimepoint: 6th & 12th month

Secondary

MeasureTime frame
1) Depressive symptoms will be assessed with Geriatric Depression Scale & Hamilton Depression Rating scale. 2) Quality of life using WHO SF-36 questionnaire. 3) Vascular and Metabolic risk factors will be assessed with blood pressure, anthropometric measurements and metabolic biomarkers through laboratory testing.Timepoint: 6th & 12th month

Countries

India

Contacts

Public ContactDr. Thomas Gregor Issac

CENTRE FOR BRAIN RESEARCH

thomasgregor@iisc.ac.in9632644712

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026