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Exploring the Analgesic Efficacy of Ketamine- Dexmedetomidine (Ketodex) in Elective Laparoscopic Cholecystectomy :A Prospective Randomised Double Blind Controlled Study

To evaluate the analgesic efficacy of Ketamine -Dexmedetomidine (Ketodex)in elective laproscopic cholecystectomy - Prospective Randomized double blind control study

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2023/07/055087
Enrollment
102
Registered
2023-07-11
Start date
Unknown
Completion date
Unknown
Last updated
2023-07-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ketamine-dexmedetomidine (KD)infusion vs Ketamine (K) infusion : Group KD Patients will be receive intravenous bolus inj Ketamine - dexmedetomidine (0.5 mg/kg + 0.5 mcg/kg) in 10 ml no

Sponsors

Indira Gandhi Institute of Medical Sciences Patna
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: AS A 1 & 2 Patients having no any co morbidities Patients willing to participate in the trial

Exclusion criteria

Exclusion criteria: ASA 3 & 4 Patients having college morbidities Patients not willing to participate in the trial

Design outcomes

Primary

MeasureTime frame
Visual analogue scale at 0 minute,30 minutes.1hr,2 hr ,4 hr ,6 hr ,8 hr ,12 hr,and 24 hr Time of first rescue analgesia (inj Tramadol ) Total does of rescue analgesia (Inj.Tramadol)Timepoint: Visual analogue scale at 0 minute,30 minutes.1hr,2 hr ,4 hr ,6 hr ,8 hr ,12 hr,and 24 hr Time of first rescue analgesia (inj Tramadol ) Total does of rescue analgesia (Inj.Tramadol)

Secondary

MeasureTime frame
1. To assess the side effects of adding ketamine & dexmedetomidine if any (nausea vomiting, & bradycardia).Timepoint: post-operatively

Countries

India

Contacts

Public ContactDr Mumtaz Hussain

Indira Gandhi institute of medical sciences, Sheikhpura,Patna

drhussain72@yahoo.co.in8544413239

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026